News & Innovations

Ziwig Endotest®

Diagnose endometriosis early and reliably with a simple saliva test

The majority of women with endometriosis experience many years of pain before getting a diagnosis. For some, getting to that stage may even require surgery.

But now a new innovation, the first of its kind in the world, can help patients avoid this suffering. A team of endometriosis doctors, artificial intelligence experts, molecular biologists and laboratory doctors have joined forces to develop a diagnostic test based on the sequencing of microRNAs found in saliva. 

This non-invasive saliva test, known as Ziwig Endotest®, was validated in the largest clinical trial ever carried out in this field4. It facilitates the early diagnostics of all forms of endometriosis4-8 with almost 100% accuracy1, 6

The distribution of Ziwig Endotest® by labor team enables doctors to diagnose and treat endometriosis at an early stage.

Endometriosis: pain and infertility

Endometriosis occurs when areas of endometrium-like tissue (the mucous membrane that covers the inside of the uterus) are found in various organs outside of the uterine cavity, such as the ovaries, vagina, rectum, bladder, bowel. During menstruation, these areas of tissue react to hormonal changes and cause inflammation, which in turn leads to significant pain and a variety of other symptoms. 

The illness can also be completely asymptomatic. In this case, it is most often diagnosed by chance when the woman visits a doctor due to struggling to conceive. A large proportion of endometriosis patients suffer from infertility.

Symptoms of endometriosis and approximate proportion of women affected12

75 – 90 %
Painful periods

30 – 40 %
Infer­tility

40 %
Pelvic pain

30 – 70 %
Pain during sexual intercourse

15 %
Extreme fatigue

30 %
Digestive disorders

3 %
Urinary tract disorders

Ziwig Endotest® and its benefits

The Ziwig Endotest® saliva test can bring down the average time to diagnosis from several years to just a few days.Klares Ergebnis

  • Clear result
  • Fast diagnosis
  • All forms of endometriosis      can be diagnosed.4-8
  • High reliability (sensitivity > 95%,  specificity > 95%, diagnostic  accuracy (AUC) > 95%)1, 6
  • Simple, non-invasive sampling

 

The bibliography and further information can be found in the following brochure:

 

You can find the profile in the analysis list here: